Medici Death

No, it wasn't the Professor in the Lounge with a revolver; it was the Cardinal in Tuscany with arsenic.

For more than four centuries, researchers have puzzled over the fact that Francesco I Medici, the son of the first Grand Duke, Cosimo, died within hours of his wife in October 1587. Legend had it they were poisoned by his brother and successor, a cardinal.
Modern historians have tended to settle for the more down-to-earth explanation that they died of malaria. But Donatella Lippi, an associate professor at the University of Florence, told the Guardian yesterday that she and other researchers had established beyond doubt that Francesco was poisoned and that evidence from "mountains of debris" underneath the deconsecrated church strongly suggested his wife was too.
...
Her search yielded part of a human liver "the size of a hazelnut" and two other body parts that have defied identification. Tests showed the liver was that of a man and its DNA matched that taken from remains in Francesco's tomb. The other body parts belonged to a woman and, like the fragment of liver, they revealed high concentrations of arsenic.
Francesco's brother, Cardinal Ferdinando, had been in danger of being excluded from the succession. In his letters to the papal court, he put the Grand Duke's illness down to his eating habits and said Bianca was sick with grief because of her husband's condition.

Sick with grief, indeed.